Extracellular matrix metalloproteinase inducer in interstitial pneumonias☆
نویسندگان
چکیده
منابع مشابه
Characteristic elevation of matrix metalloproteinase activity in idiopathic interstitial pneumonias.
Destruction of subepithelial basement membrane is a key event in the pathogenesis of idiopathic pulmonary fibrosis (IPF). To evaluate the role of matrix metalloproteinases (MMPs) in parenchymal remodeling in idiopathic interstitial pneumonia (IIP), we studied MMP-2 and -9 activity, in bronchoalveolar lavage fluid (BALF) by zymography and the expression of MMP-2 and -9 and TIMP-2 in lung tissue ...
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متن کاملcd147 (extracellular matrix metalloproteinase inducer-emmprin) expression by human articular chondrocytes
background: integrins are a family of transmembrane proteins that allow communication between the extracellular matrix and the interior of cells. chondrocytes, cells of articular cartilage, express integrins and these molecules appear to have a variety of roles including mechanotransduction. integrins are known to associate with a number of accessory molecules such as cd147 that may act to regu...
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ژورنال
عنوان ژورنال: Human Pathology
سال: 2006
ISSN: 0046-8177
DOI: 10.1016/j.humpath.2006.03.006